Articles tagged with "Alzheimer’s"


  • Your Alzheimer’s Prevention Program – Start Today!

    David Perlmutter M.D. – Empowering Neurologist: The food, the facts, the science to control your genetic destiny. It’s relatively straightforward – the best time to do something about fending off Alzheimer’s disease and dementia is well before you start to experience warning signs of cognitive decline. As has been well-documented on this blog before, inflammation in your 20s, 30s, 40s…really, at any stage in life, has been associated with increasing your risk for Alzheimer’s disease, a disease for which there is no cure. As we’ve been preparing and launching our docuseries on Alzheimer’s, Alzheimer’s: The Science of Prevention, I’ve been reminded of the importance of this, and the relationship between Alzheimer’s and inflammation, thanks to the information shared by the experts taking part in this series. So today I want to review some recent science that shows just how powerful that relationship has been revealed to be. The post Your Read More

  • How to Lower Risk for Brain Amyloid

    David Perlmutter M.D. – Empowering Neurologist: The food, the facts, the science to control your genetic destiny. It is well-documented that the accumulation of the beta-amyloid protein in the brain is correlated with Alzheimer’s disease. Ongoing research seeks to understand how, and at what stage of Alzheimer’s, beta-amyloid proteins influence the disease. What we can be certain of is that reducing levels of beta-amyloid accumulation, and preventing accumulation in the first place, is something we should be striving for in the pursuit of optimal brain health. Doing so means understanding what causes beta-amyloid accumulation in the first place. A study in the journal Nature looked at one specific factor, insulin resistance, to understand its role, and also considered it in the context of whether or not the research subject was a carrier of the APOE4 gene. The results are illuminating with regard to what they tell us about the significance Read More

  • Coffee – Good for Your Brain!

    David Perlmutter M.D. – Empowering Neurologist: The food, the facts, the science to control your genetic destiny. There has certainly been a lot of information appearing in scientific literature as of late indicating that coffee consumption is good for the brain. One recent report has revealed what I believe to be a very specific mechanism that directly relates the consumption of coffee to the well-established reduction in risk for Alzheimer’s disease (AD). Researchers in Toronto, Canada, recognizing that coffee consumption is correlated with the decreased risk of Alzheimer’s disease, set about to unravel the specific mechanism whereby coffee is neuroprotective in humans. They explored whether certain compounds found in brewed coffee can protect the brain by reducing the aggregation, or clumping, of specific proteins that occur in the brain. The aggregation of these two proteins, amyloid-beta (Aβ) and tau, seems to set the stage for brain degeneration. When this aggregation Read More

  • Implications of the “Alzheimer’s Gene” in Children

    David Perlmutter M.D. – Empowering Neurologist: The food, the facts, the science to control your genetic destiny. The development of highly accurate and widely available genome sequencing technology has put us at a crossroads. Now, more than ever, the divergent views of nature versus nurture confront consumers wishing to be advocates for their own health. As we learn about our genetics it seems quite clear that the deterministic message about our health destiny is ringing loud and clear. More and more, the idea that we are at the mercy of our inheritance seems supported by the advancing understanding and interpretation of our individual genetic profiles. An important message we have been espousing over the past decade centers on the importance of lifestyle choices, specifically directed to offset disease risk that may well be enhanced by genetics. This ideology centers on the notion of genetic predisposition in contrast to genetic determinism. Read More

  • Neurogenesis & Alzheimer’s: A Correlation?

    David Perlmutter M.D. – Empowering Neurologist: The food, the facts, the science to control your genetic destiny. If you’ve been following me for some time, you know that one area of brain health we talk about in relationship to Alzheimer’s, quite frequently, is neurogenesis. Otherwise known as the ability to grow new brain cells, neurogenesis is an incredibly powerful ability we retain as humans, especially as it relates to neurogenesis in the hippocampus. For some time, we have talked about the potential link between neurogenesis, or the lack thereof, and risk for Alzheimer’s disease, but there has been little scientific literature on which to further explore this possibility. Until now. A critically important new study looks at rates of neurogenesis and markers for Alzheimer’s disease, and sheds some light on this relationship. Let’s explore. The post Neurogenesis & Alzheimer’s: A Correlation? appeared first on David Perlmutter M.D.. Source

  • Even Mild Exercise Helps the Brain

    An important part of my lectures over the past several years has been to emphasize how our lifestyle choices, around things like sleep, diet, and exercise, will ultimately impact the destiny of our brains. For example, we have long been discussing how exercising today relates to a healthy brain in the future, especially its association with reduced risk for dementia. Now, new data is revealing that exercise not only has long-term benefits for brain health, but even more acute changes are being discovered that are clearly positive. In their recent publication in the journal PNAS, Japanese researchers, with the accepted premise that physical exercise does benefit how the brain works, wanted to determine some specifics about just how much exercise is required for it to positively impact the brain. Their human research utilized some very sophisticated, high-resolution MRI brain scanning techniques that are able to delineate the functionality of the brain’s Read More

  • Vitamin D and Alzheimer’s Disease: Could Deficiency Increase Your Risk?

    You know, we’ve explored, several times now, the relationship between vitamin D levels and risks for severe health complications, including dementia. Notably, my colleague Dr. Dale Bredesen has written and researched much on this topic, particularly with regard to the relationship between vitamin D levels and Alzheimer’s risk. In fact, Dr. Bredesen even includes vitamin D supplementation in his protocol for treating Alzheimer’s and dementia. Well, a new study in the journal Neurology explores the scientific fact behind this relationship between vitamin D, and dementia and Alzheimer’s. This longitudinal study followed 1,000+ elderly individuals who were free of dementia at the outset, to see how their vitamin D levels and brain health state changed over time. Here’s what they found. Source

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