Articles tagged with "APOE4"


  • How to Lower Risk for Brain Amyloid

    David Perlmutter M.D. – Empowering Neurologist: The food, the facts, the science to control your genetic destiny. It is well-documented that the accumulation of the beta-amyloid protein in the brain is correlated with Alzheimer’s disease. Ongoing research seeks to understand how, and at what stage of Alzheimer’s, beta-amyloid proteins influence the disease. What we can be certain of is that reducing levels of beta-amyloid accumulation, and preventing accumulation in the first place, is something we should be striving for in the pursuit of optimal brain health. Doing so means understanding what causes beta-amyloid accumulation in the first place. A study in the journal Nature looked at one specific factor, insulin resistance, to understand its role, and also considered it in the context of whether or not the research subject was a carrier of the APOE4 gene. The results are illuminating with regard to what they tell us about the significance Read More

  • Implications of the “Alzheimer’s Gene” in Children

    David Perlmutter M.D. – Empowering Neurologist: The food, the facts, the science to control your genetic destiny. The development of highly accurate and widely available genome sequencing technology has put us at a crossroads. Now, more than ever, the divergent views of nature versus nurture confront consumers wishing to be advocates for their own health. As we learn about our genetics it seems quite clear that the deterministic message about our health destiny is ringing loud and clear. More and more, the idea that we are at the mercy of our inheritance seems supported by the advancing understanding and interpretation of our individual genetic profiles. An important message we have been espousing over the past decade centers on the importance of lifestyle choices, specifically directed to offset disease risk that may well be enhanced by genetics. This ideology centers on the notion of genetic predisposition in contrast to genetic determinism. Read More

Top