Articles tagged with "Insulin Resistance"


  • How to Lower Risk for Brain Amyloid

    David Perlmutter M.D. – Empowering Neurologist: The food, the facts, the science to control your genetic destiny. It is well-documented that the accumulation of the beta-amyloid protein in the brain is correlated with Alzheimer’s disease. Ongoing research seeks to understand how, and at what stage of Alzheimer’s, beta-amyloid proteins influence the disease. What we can be certain of is that reducing levels of beta-amyloid accumulation, and preventing accumulation in the first place, is something we should be striving for in the pursuit of optimal brain health. Doing so means understanding what causes beta-amyloid accumulation in the first place. A study in the journal Nature looked at one specific factor, insulin resistance, to understand its role, and also considered it in the context of whether or not the research subject was a carrier of the APOE4 gene. The results are illuminating with regard to what they tell us about the significance Read More

  • Diabetes Risk and Impulsivity

    Understanding the relationship between less healthful dietary and lifestyle choices and developing type-2 diabetes, a recent study linking the brain’s center for impulsive behavior and diabetes risk was really interesting. The research was performed at the Massachusetts General Hospital and involved 232 non-diabetic subjects. These individuals underwent brain-imaging studies that measured the metabolic activity of their amygdalas, an area of the brain that is involved with fear, stress, and impulsivity. Researchers demonstrated that individuals with an amygdala that showed higher activity were much more likely to later develop diabetes. This risk seemed to be independent of obesity. Even the risk for insulin resistance, the harbinger for diabetes, also correlated with increased activity in the amygdala. There are a lot of interesting ideas that this relationship brings to mind. First, the amygdala is activated by stress. Stress also increases the level of cortisol hormone in the blood, which may then go Read More

  • Diabetes Risk and Impulsivity

    Understanding the relationship between less healthful dietary and lifestyle choices and developing type-2 diabetes, a recent study linking the brain’s center for impulsive behavior and diabetes risk was really interesting. The research was performed at the Massachusetts General Hospital and involved 232 non-diabetic subjects. These individuals underwent brain-imaging studies that measured the metabolic activity of their amygdalas, an area of the brain that is involved with fear, stress, and impulsivity. Researchers demonstrated that individuals with an amygdala that showed higher activity were much more likely to later develop diabetes. This risk seemed to be independent of obesity. Even the risk for insulin resistance, the harbinger for diabetes, also correlated with increased activity in the amygdala. There are a lot of interesting ideas that this relationship brings to mind. First, the amygdala is activated by stress. Stress also increases the level of cortisol hormone in the blood, which may then go Read More

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